![]() Different laboratories use combinations of engineered extracellular matrices ("scaffolds"), cells, and biologically active molecules to mimic the in vivo conditions. Scientific advances in biomaterials, stem cells, growth and differentiation factors, and biomimetic environments have created unique opportunities to fabricate or improve regenerative engineering. It starts from using cells as building blocks on scaffolds to large scale whole structures towards medicinal use. Tissue engineering brings together multiple aspects of science, medicine and engineering. The Editors of BMC Biomedical Engineering and BMC Biotechnology announce the launch and call for research articles on Tissue Engineering. He has also worked as a visiting senior research fellow at the ID3S (Implant, Device, Drug, Drug Delivery System), Translational Health Science and Technology Institute (Faridabad, India), in targeted drug delivery of anti-tubercular formulation and compartment trafficking in human pulmonary macrophages. His postdoctoral work has involved studying how to control immune reactions to biomaterials, as well as studies of decellularized matrix and bioengineered human cornea. ![]() After finishing his doctorate, he worked as a research associate at the Penn State College of Medicine (United States) and the Regenerative Engineering Laboratory at the Indian Institute of Technology (Delhi, India). Currently, he is developing in vitro disease platforms to use in regenerative medicine and the evaluation of pharmaceutical drugs. Subhadeep Roy is an assistant professor at NIPER (National Institute of Pharmaceutical Education and Research), in Kolkata (India), where he specializes in pharmacology and toxicology. Subhadeep Roy: National Institute of Pharmaceutical Education and Research (NIPER), India Kaur’s main area of research is the synthesis of NanoEngineered Injectable Hydrogels for osteoporotic vertebral bone fractures and additionally has extensive experience in bone regeneration, biomaterials science, materials science, and in vitro studies. Kulwinder Kaur is a research Fellow at Marie Skłodowska-Curie Actions (MSCA) in RCSI, Dublin. Kulwinder Kaur: Royal College of Surgeons in Ireland, Ireland Chan’s research mainly focuses on advancing biofabrication approaches and biomaterial design for stem cell tissue engineering and regenerative medicine, as well as understanding how microenvironmental cues influence stem cell proliferation and differentiation. Hon Fai Chan is an Assistant Professor at the Institute for Tissue Engineering and Regenerative Medicine and the School of Biomedical Sciences at The Chinese University of Hong Kong (CUHK). 28, 1149–1156 (1994).Hon Fai Chan: The Chinese University of Hong Kong, China Healing of large segmental defects in rat femurs is aided by RhBMP-2 in PLGA matrix. The healing of segmental bone defects induced by recombinant human bone morphogenetic protein (rhBMP-2). The ingrowth of new bone tissue and initial mechanical properties of a degrading polymeric composite scaffold. Bone formation using porous poly (lactic-co-glycolic acid) seeded with stromal osteoblast cells. Tissue-engineered growth of bone and cartilage. Osteoblast function on synthetic biodegradable polymers. Ishaug, S.L., Yaszemski, M.J., Bizios, R. Biodegradable polymer scaffolds to regenerate organs. Thompson, R.C., Wake, M.C., Yaszemski, M.J. & Caplan, A.I., Marrow cell induced osteogenesis in porous hydroxyapatite and tricalcium phosphate: A comparative histomorphometric study of ectopic bone formation. Ohgushi, H., Okumura, M., Tamai, S., Shors, E.C. Haemopoietic long-term bone marrow cultures from adult mice show osteogenic capacity in vitro on 3-dimensional collagen sponges. Characterization of cells with osteogenic potential from human marrow. Haynesworth, S.E., Goshima, J., Goldberg, V.M. Calvarial bone regeneration using osteogenin. Hollinger, J., Mark, D.E., Bach, D.E., Reddi, A.H.
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